RESUMO
We made a comparative survey of the poliovirus antibodies (anti-poliovirus type 1, anti-poliovirus type 2 and anti-poliovirus type 3) and the measles antibodies in malnourished but completely vaccinated children (37) and control children (34). The age range was 10 months to 5 years. Immunization in children with protein-energy malnutrition was low for both vaccines. Seroprevalence rates of the polio 1, polio 2, polio 3 antibodies and the measles antibodies in the control group were 94.1%, 97.1%, 91.2% and 82.4% respectively. In malnourished children the respective rates were in some cases significantly lower being: 40.5% (P = 0.001), 59.5% (P = 0.001), 40.5% and 35.1%. Malnutrition is a major determinant of the humoral response to oral polio and measles vaccines and must be given due consideration to prevent vaccination failure.
Assuntos
Transtornos da Nutrição Infantil/complicações , Sarampo/prevenção & controle , Poliomielite/prevenção & controle , Desnutrição Proteico-Calórica/complicações , Vacinação/normas , Distribuição por Idade , Anticorpos Antivirais/sangue , Formação de Anticorpos , Estudos de Casos e Controles , Criança , Transtornos da Nutrição Infantil/sangue , Transtornos da Nutrição Infantil/imunologia , Pré-Escolar , Feminino , Humanos , Esquemas de Imunização , Lactente , Masculino , Sarampo/complicações , Sarampo/epidemiologia , Vírus do Sarampo/imunologia , Marrocos/epidemiologia , Poliomielite/complicações , Poliomielite/epidemiologia , Poliovirus/imunologia , Desnutrição Proteico-Calórica/sangue , Desnutrição Proteico-Calórica/imunologia , Estudos Soroepidemiológicos , Distribuição por Sexo , Falha de TratamentoRESUMO
We made a comparative survey of the poliovirus antibodies [anti-poliovirus type 1, anti-poliovirus type 2 and anti-poliovirus type 3] and the measles antibodies in malnourished but completely vaccinated children [37] and control children [34].The age range was 10 months to 5 years. Immunization in children with protein-energy malnutrition was low for both vaccines. Seroprevalence rates of the polio 1, polio 2, polio 3 antibodies and the measles antibodies in the control group were 94.1%, 97.1%, 91.2% and 82.4% respectively. In malnourished children the respective rates were in some cases significantly lower being: 40.5% [P = 0.001], 59.5% [P = 0.001], 40.5% and 35.1%. Malnutrition is a major determinant of the humoral response to oral polio and measles vaccines and must be given due consideration to prevent vaccination failure
